A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the ...

The rapid development of spatial transcriptomics (ST) technologies has greatly advanced the understanding of gene expression, tissue architecture, cellular composition, and disease mechanisms within ...

A core challenge in biology is understanding how processes in the body, such as cellular development and regeneration, unfold ...

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Larotrectinib in Patients With Tumors With NTRK Fusions: Results From the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol EAY131-Z1E Advancements in profiling technologies have deepened our ...

Kelly Parliament, staff application scientist at Beckman Coulter Life Sciences, discusses how automation is improving the efficiency of single-cell transcriptomic workflows. Single-cell ...

Spatial and single-cell analyses of human donor pancreata showed that PanIN epithelial cells gradually acquire cancer-like ...

RNA sequencing (RNA-Seq): A high-throughput transcriptomics method that identifies and quantifies RNA molecules in a biological sample by converting them into sequencing libraries, or in some ...

Using spatial multi-omics, researchers identified shifting macrophage populations in MASLD progression, identifying markers to aid patient stratification in clinical trials.

Integrated mass spectrometry imaging and spatial transcriptomics reveal that amyloid-β plaques differ in composition and local tissue responses, offering insight into Alzheimer’s disease heterogeneity ...